SCABERASE
SPECIFICATIONS OF SCABERASE TABLETS
Product Name
SCABERASE-IM Tabs.
SCABERASE-IF Tabs.
Ingredients & Pack
Ivermectin-6mg. Blister 1’s pack . Box 25x1’s
Tablet colour – Titanium dioxide
Ivermectin-12mg. Blister 1’s pack. Box 25x1’s
Tablet colour- Brilliant Blue
Special Features
Effective, Convenient Anti-parasitic
Following oral administration of Iveremctin, peak plasma conc.( 46ng/ml after single 12mg dose) is achieved in 4 hrs
The bioavailability of solid forms of Iveremctin is around 50-60%.
It is mainly metabolized in liver and tissue conc. is max. in liver and fat.
Iveremctin and its metabolite are excreted mainly in feces (95%) over an estimated period of 12 days.
Alternate to Topical Anti-Scabies Agents.
Technical Specification
Ivermectin is a semi synthetic derivative of one of the avermectins, a group of macrocyclic lactones produced by Streptomyces avermitilis.
Ivermectin is a member of the avermectin class of broad spectrum anti parasitic agent, which binds to glutamate gated or GABA gated chloride ion channels which occur in invertebrate nerve and muscle cells.
This leads to an increase in the permeability of cell membrane to chloride ions with hyperpolarisation of nerve of muscle cell, resulting in paralysis & death of parasite.